Evidence synthesis and different types of reviews

Evidence syntheses combine data from multiple sources, most commonly from existing research studies, to provide an overall summary of current knowledge.

Evidence syntheses vs primary study

There is a difference between syntheses and primary studies. Syntheses sum up primary studies. But there are also synopses of syntheses.

Study designs

Studytype Scope Quality
Direct observation Direct measurement highest
Meta-analysis Synopses of syntheses high
Systematic review Syntheses high
Evidence syntheses Syntheses high
RCT Experimental medium
Laboratory Experimental medium
Cohort Observational medium
Case control Observational medium
Cross sectional Observational medium
Case series Descriptive medium
Qualitative studies Primary study medium
Systematic expert opinion Primary study medium
Unystematic expert opinion Primary study medium

A more detailled listing of evidence synthesis

  • Rapid review: Rapidly summarize and synthesize existing evidence often for time-sensitive decision-making
  • Literature review: Provide a broad overview of existing literature on a topic.
  • Scoping review: Map and asses the extent of existing research on a broad topic often without specific research questions to identify key concepts, sources and gaps
  • Systematic review: Answer a specific research question by systematically collecting, evaluating and synthesizing existing research studies
  • Systematic review with meta-analysis: A meta-analysis is a quantitative, formal and epidemiological study design used to systematically assess the results of previous research to derive conclusions.
  • Umbrella review: Synthesize findings from multiple systematic reviews and meta-analyses on a specific topic
  • Living review: A review article that is updated at intervals to reflect the latest research